Mycoses and onychomycoses of feet caused by dermatomycetes are extremely widespread and often relapse. Although there are quite a lot of modern antifungal medications, effective at dermatomycetes treatment, therapy usually takes a long time because infected footwear often becomes the source of a repeated infection.  The choice of footwear disinfection means is quite limited. As a rule, it is suggested to use formalin solution (25%) which has an unpleasant smell and is toxic enough; otherwise it is recommended to dispose of footwear after the treatment is finished.

It is known that ultra-violet (UV) radiation has a destructive impact on microorganisms, including yeast and dermatomycetes. Kashkin Research Institute of Medical Mycology performed the research of a Quartz-Mercury Lamp-2 impact on Candida spp. It was established that radiation in the amount of 1/2-8 biodoses has an intense fungicide effect on Candida albicans, S. to krusei, S. tropicalis and C. kefyr.

Based on the data about anti-fungal activity of UV-radiation, Timson LLC developed the footwear UV anti-fungal treatment device. The device consists of 4 UV-lamps and the heater.

Objective of the research is to study the influence of Timson UV anti-fungal treatment device on fungi — dermatomycetes and S. albicans in the course of experiment.

RESULTS AND DISCUSSION

It is remarkable that all test bacterial cultures on footwear insoles died within 8- and 12-hour impact of the device respectively. During assessment of all the test cultures under examination the result is statistically reliable P < 0.03 according to the complex of the nonparametric criteria used.

2-hour impact of the device on the test culture did not affect fungi survival; its growth is similar to that of other control dish. 4-hour impact of the device was accompanied by dramatic reduction of survived cells
number (0,0015%). 6-8-hour impact resulted in full elimination of T. rubrum cells.

Thus, Timson UV anti-fungal treatment device has an intense fungicide effect on C.albicans, ‘T.rubrum, T.mentagrophytes fungi. Exposure of experimentally infected footwear insoles for the device within 4 hours caused dramatic reduction of T.rubrum RKPGF-1231 viable cells number, within 8-12 hours led to a 100% elimination of cells of all studied strains of C.albicans, T.rubrum and T.mentagrophytes. The result is statistically reliable — P < 0.04 according to the complex of the nonparametric criteria used.

CONCLUSIONS

Timson UV anti-fungal treatment device has an intense fungicide effect on the principal athlete’s foot cause fungi and thus it can be recommended for treatment of footwear of patients suffering from athlete’s foot as a preventive measure, as well as a means for preventing relapses. Moreover, the device has a strong odour-removing and drying effect.

PROBLEMS OF THE MEDICAL MYCOLOGY, 2007. ED.9 №2

UDC616.992
The efficiency of TIMSON footwear anti-fungal treatment device to some pathogenic fungi

N.V. Vasilyeva , G.A. Chilina , T.S. Bogomolova 
Kashkin Research Institute of Medical Mycology, SEI APE SPb. MAPE, Russia
© G.A. Chilina , T.S. Bogomolova , 2007 
This article presents the results of laboratory investigations on efficiency of TIMSON footwear anti-fungal treatment device to Candida albicans, Trichophyton rubrum and T. mentagrophytes. A strong antifungal effect of the device has been revealed,
especially in cases of treatment of footwear contaminated with above-listed fungi. The device is recommended for treatment of footwear of patients suffering from athlete’s foot as a preventive measure, as well as a means for preventing relapses.
Key words: dermatomycetes, Candida, shoes, ultraviolet radiation.